Cipro (Ciprofloxacin): instructions for use, dosage, composition. Online order.

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CIPRO

ACTIVE INGREDIENT: CIPROFLOXACIN

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Effectiveness of Cipro against bacteria

Ciprofloxacin is a strong antimicrobial drug from the group of fluoroquinolones. A quinolone derivative that inhibits bacterial DNA gyrase, disrupts DNA synthesis, growth and division of bacteria. Causes pronounced morphological changes and rapid death of the bacterial cell. It acts bactericidal on gram-negative organisms during dormancy and division, on gram-positive microorganisms only during division. This allows the use of Ciprofloxacin, both in outpatient (out-of-hospital) conditions and in professional clinics.

Ciprofloxacin tablet is rapidly absorbed into the walls of the rectum, after which it is distributed in the tissues and body fluids. 70% of the drug when using Ciprofloxacin, according to the instructions, is excreted during the first couple of days, along with urine and bile. The maximum concentration of the drug is observed in bile secretions.

According to the instructions for use, Ciprofloxacin tablets are an indispensable tool for complex therapy after surgery. The use of Ciprofloxacin avoids postoperative infection, prevents the focus of the spread of the inflammatory process, and stops inflammation in the initial stage. Before using Ciprofloxacin tablets according to the instructions for this purpose, you should first find out if the patient has intolerance to any component of this drug.

Infectious diseases of bones and joints (with the exception of tuberculosis and genital infections) are also indications for treatment with Ciprofloxacin according to the instructions for its use. In such cases, treatment is recommended to begin with surgery and continue with restorative therapy. Treatment is prescribed based on the patient's indications / contraindications to the components of the drug. In cases of nosocomial infection of the patient, therapy with several antibiotics may be prescribed.

In inflammatory diseases of the small pelvis, sexual infections are often the root cause in combination with aerobic gram-negative, gram-positive and anaerobic microflora. The causative agents can be both “typical” gonococci and their other “atypical” representatives, in such cases, the use of Ciprofloxacin according to the instructions should be combined with other antibiotics for greater treatment efficiency.

For example, the combination of drugs such as Doxycycline and Metronidazole, together with the specified antibiotic for 14 days, gives an efficiency level of 88-98%. And in other studies, therapy combined Ciprofloxacin tablets according to the instructions and Doxycycline and the effectiveness rate was 95-97%. This proves the maximum effectiveness of the drug for the treatment of such infections, both alone and in combination with other antibiotics.

How does Cipro work?

Ciprofloxacin is a broad-spectrum antimicrobial drug from the group of fluoroquinolones. Acts bactericidal. The drug inhibits the enzyme DNA-gyrase of bacteria, as a result of which DNA replication and the synthesis of cellular proteins of bacteria are disrupted.

What infections does ciprofloxacin treat?

Infectious and inflammatory diseases caused by microorganisms sensitive to ciprofloxacin, including diseases of the respiratory tract, abdominal cavity and pelvic organs, bones, joints, skin; septicemia; severe infections of the upper respiratory tract. Treatment of postoperative infections.

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Form of release and composition

Capsule-shaped tablets with a biconvex surface, film-coated white or almost white. White in cross section.

Tablets 250mg, 500mg, 750mg, 1000mg.

Active substance: ciprofloxacin hydrochloride monohydrate.

Excipients: microcrystalline cellulose (73.5 mg/147.0 mg), low molecular weight povidone (8.75 mg/17.5 mg), potato starch (7.0 mg/14.0 mg), magnesium stearate (1.75 mg / 3.5 mg), lactose monohydrate (up to 175.0 mg / up to 350.0 mg).

Indications for use

- infectious diseases, passing in an acute form;

- diseases of the bronchi and lungs;

- diseases of the abdominal cavity and small pelvis;

- diseases of the skeleton and joints;

- skin lesions;

- purulent inflammation, risking to turn into blood poisoning;

- infections of the upper respiratory tract, passing in an acute form;

- infections that occurred as complications after surgery;

- surgical treatment and prevention of infections for persons with a low threshold of immunity;

Ciprofloxacin 500: instructions and features of the appointment

In the instructions for Ciprofloxacin 500 mg tablets, it is indicated that this drug can be used for antibacterial therapy of a wide range of diseases. Since the antibiotic can affect the state of the internal organs, Ciprofloxacin 500 tablets should be taken under the supervision of a physician and additional blood tests should be regularly performed to monitor the functions of other systems.

Any deviation from the instructions for Cyclofloxacin 500 is fraught with consequences. To prevent negative reactions from the body, strictly follow the recommendations of the doctor and do not deviate from the treatment regimen developed by him. The full range of diseases for which Ciprofloxacin 500 is prescribed is indicated in the instructions.

Method of application and dosage

Ciprofloxacin tablets should be swallowed whole with a small amount of liquid. On an empty stomach or after a meal. When taking Ciprofloxacin tablets on an empty stomach, the active substance is absorbed faster.

In the instructions for use of Ciprofloxacin tablets, the following recommended dosages and regimens are indicated:

For mild to moderate lower respiratory tract infections, take 0.5 grams 2 times a day. With the same severe infections - 0.75 grams 2 times a day. The course of treatment is 7-14 days.

In acute sinusitis, take 0.5 grams 2 times a day. The course of treatment is 10 days.

For mild to moderate infections of the skin and soft tissues, take 0.5 grams 2 times a day, for severe infections - 0.75 grams 2 times a day. The course of treatment is 7-14 days.

For infections of the bones and joints, Ciprofloxacin should be taken: for mild and moderate - 0.5 grams 2 times a day, for severe cases - 0.75 grams 2 times. The course of treatment is up to 4-6 weeks.

For uncomplicated urinary tract infections, take 0.25-0.5 grams 2 times a day. The course of treatment is 7-14 days, with complicated urinary tract infections, 0.5 grams should be taken every 12 hours for 7-14 days.

For chronic prostatitis, take 0.5 grams 2 times. The course of treatment is 28 days.

For uncomplicated gonorrhea, take 0.25 grams once.

In acute intestinal infections with severe course (salmonellosis, shigellosis, campylobacteriosis, etc.), you should take Ciprofloxacin 0.5 grams 2 times. The course of treatment is 5-7 days.

For typhoid fever, take 0.5 grams 2 times. The course of treatment is 10 days.

For complicated intra-abdominal infections, take 0.5 grams every 12 hours. The course is 7-14 days.

For the prevention and treatment of the pulmonary form of anthrax, take 0.5 grams 2 times a day for 60 days.

In patients with immunodeficiency, treatment is prescribed depending on the severity of the infection and the type of pathogen. Therapy is carried out during the entire period of neutropenia.

For patients with chronic renal failure: with a creatinine clearance (CC) of more than 50 ml / min, dose adjustment is not required. With CC 30-50 ml / min, 0.25-0.5 grams should be taken every 12 hours. With CC 5-29 ml / min, 0.25-0.5 g should be taken every 18 hours. If the patient undergoes hemodialysis or peritoneal dialysis, it is necessary to take 0.25-0.5 grams per day, the drug should be taken after a hemodialysis session.

According to the instructions for use, Ciprofloxacin tablets are an indispensable tool for complex therapy after surgery. The use of Ciprofloxacin avoids postoperative infection, prevents the focus of the spread of the inflammatory process, and stops inflammation in the initial stage. Before using Ciprofloxacin tablets according to the instructions for this purpose, you should first find out if the patient has intolerance to any component of this drug.

Infectious diseases of bones and joints (with the exception of tuberculosis and genital infections) are also indications for treatment with Ciprofloxacin according to the instructions for its use. In such cases, treatment is recommended to begin with surgery and continue with restorative therapy. Treatment is prescribed based on the patient's indications / contraindications to the components of the drug. In cases of nosocomial infection of the patient, therapy with several antibiotics may be prescribed.

In inflammatory diseases of the small pelvis, sexual infections are often the root cause in combination with aerobic gram-negative, gram-positive and anaerobic microflora. The causative agents can be both “typical” gonococci and their other “atypical” representatives, in such cases, the use of Ciprofloxacin according to the instructions should be combined with other antibiotics for greater treatment efficiency.

For example, the combination of drugs such as Doxycycline and Metronidazole, together with the specified antibiotic for 14 days, gives an efficiency level of 88-98%. And in other studies, therapy combined Ciprofloxacin tablets according to the instructions and Doxycycline and the effectiveness rate was 95-97%. This proves the maximum effectiveness of the drug for the treatment of such infections, both alone and in combination with other antibiotics.

Possible side effects of Ciprofloxacin tablets:

Nausea and vomiting, severe diarrhea, stomach pain, increased activity of hepatic transaminases, alkaline phosphatase, lactate dehydrogenase, increased excretion of bile from the body, acute inflammation of the large intestine.

Severe migraines, dizziness, chronic fatigue, insomnia, disturbing dreams, hallucinations, fainting, marked visual impairment.

Violation of the process of excretion of salts and sand, damage to the glomeruli in the kidneys, disruption of the kidneys, progression of pathologies of the kidneys and urinary tract, an increase in the content of creatinine in the blood.

Increase in the number of eosinophils, decrease in the number of leukocytes in the blood, neutropenic fever, changes in the number of platelets.

The development of tachycardia, cardiac arrhythmias, lowering blood pressure.

Skin itching, redness, angioedema, Stevens-Johnson syndrome, joint pain, fungal infection.

General condition of pain, damage to important blood lines (when the drug is administered intravenously).

Drug interaction

Caution should be exercised while using ciprofloxacin and drugs metabolized by these enzymes, such as theophylline, methylxanthine, caffeine, duloxetine, ropinirole, clozapine, olanzapine, agomelatine - because. an increase in the concentration of these drugs in the blood serum, due to the inhibition of their metabolism by ciprofloxacin, can cause specific adverse reactions. The simultaneous use of ciprofloxacin and tizanidine is contraindicated.

Storage conditions

The drug should be stored in a place protected from light at a temperature of 5 ° to 20 ° C, out of the reach of children. Do not freeze!

Terms of dispensing from pharmacies

In city pharmacies: by prescription.

In online pharmacies you can buy Cipro without a prescription.

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